Dein Suchergebnis zum Thema: Model

Launch of Start-up QLi5 Therapeutics

https://www.mpg.de/14956262/launch-of-start-up-qli5-therapeutics

The Lead Discovery Center GmbH (LDC) and the South Korean drug development specialist Qurient have founded QLi5 Therapeutics GmbH, together with the LDC’s partners, the Max Planck Society (MPG) and Nobel laureate Prof. Huber, emeritus director of the Max Planck Institute for Biochemistry. Dortmund based QLi5 Therapeutics licensed novel proteasome inhibitors from LDC and its partners. QLi5 Therapeutics will advance these towards preclinical and clinical development for the treatment of cancers and inflammatory and autoimmune disorders.
cylinder consisting of 28 subunits, which are shown in color here in the ligament model

How the modular structure of proteins permits evolution to move forward

https://www.mpg.de/4377732/signalling_pathways_evolution?page=2

Changes in a short protein domain can alter a whole signaling network involved in organ development – this is the key result of a comparative study of the development of the egg laying organ in two species of nematodes. However, the outward appearance of the organ remains the same in both species. The study provides support for the theory of developmental systems drift – a theory maintaining that, over the course of evolution, analogous organs of different species can retain the same shape and function while the regulative mechanisms underlying their development can change considerably.
Pristionchus pacificus (P. pacificus), established as a model system in evolutionary