Dein Suchergebnis zum Thema: Gen

.: Flowers with bad breath: How an old gene acquired a new function to exploit an

glucosinolate hydrolysis products, rescuing a commensal that suppresses virulence gene

.: Flowers with bad breath: How an old gene acquired a new function to exploit an

glucosinolate hydrolysis products, rescuing a commensal that suppresses virulence gene

.: Metabolic novelty originating from horizontal gene transfer is essential for leaf

The biosynthesis of the great variety of natural plant products has not yet been elucidated for many medically interesting substances. In a new study, an international team of researchers was able to show how ipecacuanha alkaloids, substances used in traditional medicine, are synthesized. They compared two distantly related plant species and were able to show that although both plant species use a comparable chemical approach, the enzymes they need for synthesis differ and a different starting material is used. Further investigations revealed that the biosynthetic pathways of these complex chemical compounds have developed independently in the two species. These results help to enable the synthesis of these and related substances on a larger scale for medical use.
By comparing tissues with high and low levels of ipecac alkaloids, genes that could

.: Glutamine as sole nitrogen source prevents induction of nitrate transporter gene

.: Flowers with bad breath: How an old gene acquired a new function to exploit an

The biosynthesis of the great variety of natural plant products has not yet been elucidated for many medically interesting substances. In a new study, an international team of researchers was able to show how ipecacuanha alkaloids, substances used in traditional medicine, are synthesized. They compared two distantly related plant species and were able to show that although both plant species use a comparable chemical approach, the enzymes they need for synthesis differ and a different starting material is used. Further investigations revealed that the biosynthetic pathways of these complex chemical compounds have developed independently in the two species. These results help to enable the synthesis of these and related substances on a larger scale for medical use.
By comparing tissues with high and low levels of ipecac alkaloids, genes that could

Die Biosynthese der großen Vielfalt von pflanzlichen Naturprodukten ist auch für viele medizinisch interessante Stoffe noch nicht aufgeklärt. Ein internationales Team von Forscherinnen und Forschern konnte in einer neuen Studie zeigen, wie Ipecacuanha-Alkaloide, Substanzen, die in der traditionellen Medizin Verwendung finden, gebildet werden. Dabei verglichen sie zwei weit entfernte Pflanzenarten und konnten zeigen, dass beide Pflanzenarten zwar einen vergleichbaren chemischen Ansatz nutzen, sich aber die Enzyme, die sie für die Synthese brauchen, unterscheiden und auch ein anderer Ausgangsstoff Verwendung findet. Weitere Untersuchungen ergaben, dass sich die Biosynthesewege dieser komplexen chemischen Verbindungen in den beiden Arten unabhängig voneinander entwickelt haben. Diese Ergebnisse helfen, die Produktion dieser und verwandter Stoffe für die Medizin in größerem Maßstab zu ermöglichen.
Vergleich von Geweben mit hohen und niedrigen Ipecacuanha-Alkaloidgehalten konnten Gene